Increase or expand the volume of plasma, the liquid part of blood (diluting the blood), such as congestive heart failure.

Increase the breakdown or loss of protein, such as kidney disease (nephrotic syndrome).

Interfere with production of albumin or globulin proteins, such as malnutrition or severe liver disease.Total protein levels may decrease in conditions that: Total protein levels in the blood may increase or decrease, to a greater or lesser degree, with various conditions. A change in this ratio can provide your healthcare practitioner with a clue as to the cause of the change in protein levels. The test also compares the amount of albumin with globulin and calculates what is called the A/G ratio.

They help fight infection and transport nutrients. The globulins are a varied group of proteins, some produced by the liver and some by the immune system. Globulins make up the remaining 40% of proteins in the blood.Albumin keeps fluid from leaking out of blood vessels, nourishes tissues, and transports hormones, vitamins, drugs, and substances like calcium throughout the body.

Albumin is made by the liver and makes up about 60% of the total protein.

Two classes of proteins are found in the blood, albumin and globulin. This test measures the amount of protein in your blood. They form the structural part of most organs and make up enzymes and hormones that regulate body functions. They are important for body growth, development, and health. Proteins are important building blocks of all cells and tissues.

Ag ratio high